Sterol regulatory element-binding protein 1

UniProtKB accession:  Q9UUD1

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UniProtKB description:  Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 1), which is embedded in the endoplasmic reticulum membrane (PubMed:15797383). Low oxygen or sterol conditions promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes required for adaptation to anaerobic growth (PubMed:15797383).