Structural basis of Nav1.7 inhibition by a gating-modifier spider toxin
External Resource: Annotation
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
| Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
|---|
| E | SCOP2B Superfamily | omega toxin-like | 8082346 | 3000255 | SCOP2B (2022-06-29) |
| F | SCOP2B Superfamily | omega toxin-like | 8082346 | 3000255 | SCOP2B (2022-06-29) |
| G | SCOP2B Superfamily | omega toxin-like | 8082346 | 3000255 | SCOP2B (2022-06-29) |
| H | SCOP2B Superfamily | omega toxin-like | 8082346 | 3000255 | SCOP2B (2022-06-29) |
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|
| A | PF00520 | e6n4iA1 | A: alpha complex topology | X: Voltage-gated ion channels (From Topology) | H: Voltage-gated ion channels (From Topology) | T: Voltage-gated ion channels | F: PF00520 | ECOD (1.6) |
| B | PF00520 | e6n4iB1 | A: alpha complex topology | X: Voltage-gated ion channels (From Topology) | H: Voltage-gated ion channels (From Topology) | T: Voltage-gated ion channels | F: PF00520 | ECOD (1.6) |
| C | PF00520 | e6n4iC1 | A: alpha complex topology | X: Voltage-gated ion channels (From Topology) | H: Voltage-gated ion channels (From Topology) | T: Voltage-gated ion channels | F: PF00520 | ECOD (1.6) |
| D | PF00520 | e6n4iD1 | A: alpha complex topology | X: Voltage-gated ion channels (From Topology) | H: Voltage-gated ion channels (From Topology) | T: Voltage-gated ion channels | F: PF00520 | ECOD (1.6) |
| E | F_UNCLASSIFIED | e6n4iE1 | A: few secondary structure elements | X: omega toxin-like | H: omega toxin-related | T: omega toxin-related | F: F_UNCLASSIFIED | ECOD (1.6) |
| F | F_UNCLASSIFIED | e6n4iF1 | A: few secondary structure elements | X: omega toxin-like | H: omega toxin-related | T: omega toxin-related | F: F_UNCLASSIFIED | ECOD (1.6) |
| G | F_UNCLASSIFIED | e6n4iG1 | A: few secondary structure elements | X: omega toxin-like | H: omega toxin-related | T: omega toxin-related | F: F_UNCLASSIFIED | ECOD (1.6) |
| H | F_UNCLASSIFIED | e6n4iH1 | A: few secondary structure elements | X: omega toxin-like | H: omega toxin-related | T: omega toxin-related | F: F_UNCLASSIFIED | ECOD (1.6) |
| Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
|---|
| Nav1.7 VSD2-NavAb channel chimera protein | - | - | - |
| Beta/omega-theraphotoxin-Tp2a | | - | |
