Annotations: 5JXT

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth B]	PF00176,PF00271	e5jxtB1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
B [auth E]	PF00176,PF00271	e5jxtE1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
C [auth F]	PF00176,PF00271	e5jxtF1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
D [auth G]	PF00176,PF00271	e5jxtG1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
E [auth J]	PF00176,PF00271	e5jxtJ1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
F [auth N]	PF00176,PF00271	e5jxtN1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
G [auth O]	PF00176,PF00271	e5jxtO1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
H [auth P]	PF00176,PF00271	e5jxtP1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
L [auth C]	PF00176,PF00271	e5jxtC1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
M [auth H]	PF00176,PF00271	e5jxtH1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
N [auth K]	PF00176,PF00271	e5jxtK1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
O [auth L]	PF00176,PF00271	e5jxtL1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
Q [auth I]	PF00176,PF00271	e5jxtI1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
P [auth A]	PF00176,PF00271	e5jxtA1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)
R [auth D]	PF00176,PF00271	e5jxtD1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00176,PF00271	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth B]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
B [auth E]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
C [auth F]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
D [auth G]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
E [auth J]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
F [auth N]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
G [auth O]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
H [auth P]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
L [auth C]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
M [auth H]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
N [auth K]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
O [auth L]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
Q [auth I]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
S [auth M]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
P [auth A]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
R [auth D]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	PF00271	Helicase conserved C-terminal domain (Helicase_C)	Helicase conserved C-terminal domain	The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.	Domain
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	PF00176	SNF2-related domain (SNF2-rel_dom)	SNF2-related domain	This domain is found in proteins involved in a variety of processes including transcription regulation (e.g., SNF2, STH1, brahma, MOT1), DNA repair (e.g., ERCC6, RAD16, RAD5), DNA recombination (e.g., RAD54), and chromatin unwinding (e.g., ISWI) as w ...	This domain is found in proteins involved in a variety of processes including transcription regulation (e.g., SNF2, STH1, brahma, MOT1), DNA repair (e.g., ERCC6, RAD16, RAD5), DNA recombination (e.g., RAD54), and chromatin unwinding (e.g., ISWI) as well as a variety of other proteins with little functional information (e.g., lodestar, ETL1)[1,2,3]. SNF2 functions as the ATPase component of the SNF2/SWI multisubunit complex, which utilises energy derived from ATP hydrolysis to disrupt histone-DNA interactions, resulting in the increased accessibility of DNA to transcription factors.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	Chromatin-remodeling complex ATPase-like protein	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding DNA binding nucleic acid binding hydrolase activity catalytic activity protein-containing complex binding chromatin binding nucleosome binding ATP-dependent activity, acting on DNA ATP-dependent chromatin remodeler activity catalytic activity, acting on DNA catalytic activity, acting on a nucleic acid ATP-dependent activity	-	membrane-bounded organelle intracellular organelle intracellular anatomical structure organelle nucleus intracellular membrane-bounded organelle cellular anatomical entity
I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], V, W	Histone H4	DNA binding binding organic cyclic compound binding nucleic acid binding protein heterodimerization activity protein binding protein dimerization activity structural molecule activity structural constituent of chromatin	-	membrane cellular anatomical entity protein-containing complex intracellular anatomical structure protein-DNA complex nucleosome chromatin chromosome intracellular organelle organelle intracellular non-membrane-bounded organelle non-membrane-bounded organelle membrane-bounded organelle nucleus membrane cellular anatomical entity protein-containing complex intracellular anatomical structure protein-DNA complex nucleosome chromatin chromosome intracellular organelle organelle intracellular non-membrane-bounded organelle non-membrane-bounded organelle membrane-bounded organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR000330	SNF2, N-terminal	Domain
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR015195	SLIDE domain	Domain
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR001650	Helicase, C-terminal domain-like	Domain
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR044754	Isw1/2, N-terminal	Domain
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR014001	Helicase superfamily 1/2, ATP-binding domain	Domain
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR009057	Homeobox-like domain superfamily	Homologous Superfamily
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR036306	ISWI, HAND domain superfamily	Homologous Superfamily
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR017884	SANT domain	Domain
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR001005	SANT/Myb domain	Domain
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR049730	SNF2/RAD5-like, C-terminal helicase domain	Domain
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR015194	ISWI, HAND domain	Domain
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR038718	SNF2-like, N-terminal domain superfamily	Homologous Superfamily
A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], A [auth B], B [auth E], C [auth F], D [auth G], E [auth J], F [auth N], G [auth O], H [auth P], L [auth C], M [auth H], N [auth K], O [auth L], P [auth A], Q [auth I], R [auth D], S [auth M]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], V, W	IPR009072	Histone-fold	Homologous Superfamily
I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], V, W	IPR008030	NmrA-like domain	Domain
I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], V, W	IPR036291	NAD(P)-binding domain superfamily	Homologous Superfamily
I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], V, W	IPR016181	Acyl-CoA N-acyltransferase	Homologous Superfamily
I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], V, W	IPR001951	Histone H4	Family
I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], I [auth R], J [auth S], K [auth U], T [auth Q], U [auth T], V, W	IPR019809	Histone H4, conserved site	Conserved Site

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.