5DN6

ATP synthase from Paracoccus denitrificans

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
J [auth G]	SCOP2 Family	ATP synthase gamma subunit-like	8072556	4000503	SCOP2 (2022-06-29)
J [auth G]	SCOP2 Superfamily	ATP synthase gamma subunit-like	8072557	3000451	SCOP2 (2022-06-29)
L [auth I]	SCOP2 Family	Epsilon subunit of F1F0-ATP synthase N-terminal domain	8097019	4003026	SCOP2 (2022-06-29)
L [auth I]	SCOP2 Superfamily	Epsilon subunit of F1F0-ATP synthase N-terminal domain	8097020	3000182	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
AA [auth X]	PF00119	e5dn6X1	A: alpha bundles	X: F1F0 ATP synthase subunit A (From Topology)	H: F1F0 ATP synthase subunit A (From Topology)	T: F1F0 ATP synthase subunit A	F: PF00119	ECOD (1.6)
CA [auth Z]	PF07345	e5dn6Z1	A: alpha duplicates or obligate multimers	X: Uncharacterized protein YP_510488.1 (From Topology)	H: Uncharacterized protein YP_510488.1 (From Topology)	T: Uncharacterized protein YP_510488.1	F: PF07345	ECOD (1.6)
E [auth B]	PF02874	e5dn6B1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02874	ECOD (1.6)
E [auth B]	PF00306	e5dn6B3	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: PF00306	ECOD (1.6)
E [auth B]	PF00006	e5dn6B2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00006	ECOD (1.6)
F [auth C]	PF02874	e5dn6C1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02874	ECOD (1.6)
F [auth C]	PF00306	e5dn6C3	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: PF00306	ECOD (1.6)
F [auth C]	PF00006	e5dn6C2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00006	ECOD (1.6)
D [auth A]	PF02874	e5dn6A3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02874	ECOD (1.6)
D [auth A]	PF00306	e5dn6A2	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: PF00306	ECOD (1.6)
D [auth A]	PF00006	e5dn6A1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00006	ECOD (1.6)
G [auth D]	PF02874	e5dn6D3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02874	ECOD (1.6)
G [auth D]	PF22919	e5dn6D1	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: PF22919	ECOD (1.6)
G [auth D]	PF00006	e5dn6D2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00006	ECOD (1.6)
H [auth E]	PF02874	e5dn6E3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02874	ECOD (1.6)
H [auth E]	PF22919	e5dn6E1	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: PF22919	ECOD (1.6)
H [auth E]	PF00006	e5dn6E2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00006	ECOD (1.6)
I [auth F]	PF02874	e5dn6F1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF02874	ECOD (1.6)
I [auth F]	PF22919	e5dn6F2	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: PF22919	ECOD (1.6)
I [auth F]	PF00006	e5dn6F3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00006	ECOD (1.6)
J [auth G]	PF00231	e5dn6G1	A: a/b three-layered sandwiches	X: ATP synthase (F1-ATPase), gamma subunit (From Topology)	H: ATP synthase (F1-ATPase), gamma subunit (From Topology)	T: ATP synthase (F1-ATPase), gamma subunit	F: PF00231	ECOD (1.6)
K [auth H]	PF00213	e5dn6H1	A: alpha bundles	X: ATPD N-terminal domain-like	H: N-terminal domain of the delta subunit of the F1F0-ATP synthase (From Topology)	T: N-terminal domain of the delta subunit of the F1F0-ATP synthase	F: PF00213	ECOD (1.6)
L [auth I]	PF02823	e5dn6I1	A: beta sandwiches	X: Epsilon subunit of F1F0-ATP synthase-N	H: Epsilon subunit of F1F0-ATP synthase-N (From Topology)	T: Epsilon subunit of F1F0-ATP synthase-N	F: PF02823	ECOD (1.6)
M [auth J]	PF00137	e5dn6J1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
N [auth K]	PF00137	e5dn6K1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
O [auth L]	PF00137	e5dn6L1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
P [auth M]	PF00137	e5dn6M1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
Q [auth N]	PF00137	e5dn6N1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
R [auth O]	PF00137	e5dn6O1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
S [auth P]	PF00137	e5dn6P1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
T [auth Q]	PF00137	e5dn6Q1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
U [auth R]	PF00137	e5dn6R1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
V [auth S]	PF00137	e5dn6S1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
W [auth T]	PF00137	e5dn6T1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)
X [auth U]	PF00137	e5dn6U1	A: extended segments	X: F1F0 ATP synthase subunit C (From Topology)	H: F1F0 ATP synthase subunit C (From Topology)	T: F1F0 ATP synthase subunit C	F: PF00137	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
E [auth B]	2.40.30.20	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)
E [auth B]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
E [auth B]	1.20.150.20	Mainly Alpha	Up-down Bundle	Lysin	ATP synthase alpha/beta chain, C-terminal domain	CATH (4.3.0)
F [auth C]	2.40.30.20	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)
F [auth C]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
F [auth C]	1.20.150.20	Mainly Alpha	Up-down Bundle	Lysin	ATP synthase alpha/beta chain, C-terminal domain	CATH (4.3.0)
D [auth A]	2.40.30.20	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)
D [auth A]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
D [auth A]	1.20.150.20	Mainly Alpha	Up-down Bundle	Lysin	ATP synthase alpha/beta chain, C-terminal domain	CATH (4.3.0)
G [auth D]	2.40.10.170	Mainly Beta	Beta Barrel	Thrombin, subunit H		CATH (4.3.0)
G [auth D]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
G [auth D]	1.10.1140.10	Mainly Alpha	Orthogonal Bundle	Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain	Chain D, domain3	CATH (4.3.0)
H [auth E]	2.40.10.170	Mainly Beta	Beta Barrel	Thrombin, subunit H		CATH (4.3.0)
H [auth E]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
H [auth E]	1.10.1140.10	Mainly Alpha	Orthogonal Bundle	Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain	Chain D, domain3	CATH (4.3.0)
I [auth F]	2.40.10.170	Mainly Beta	Beta Barrel	Thrombin, subunit H		CATH (4.3.0)
I [auth F]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
I [auth F]	1.10.1140.10	Mainly Alpha	Orthogonal Bundle	Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain	Chain D, domain3	CATH (4.3.0)
J [auth G]	1.10.287.80	Mainly Alpha	Orthogonal Bundle	Helix Hairpins	ATP synthase, gamma subunit, helix hairpin domain	CATH (4.3.0)
J [auth G]	3.40.1380.10	Alpha Beta	3-Layer(aba) Sandwich	Pyruvate Kinase	Chain: A, domain 1	CATH (4.3.0)
L [auth I]	2.60.15.10	Mainly Beta	Sandwich	ATP Synthase	domain 1	CATH (4.3.0)
M [auth J]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)
N [auth K]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)
O [auth L]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)
P [auth M]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)
Q [auth N]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)
R [auth O]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)
S [auth P]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)
T [auth Q]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)
U [auth R]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)
V [auth S]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)
W [auth T]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)
X [auth U]	1.20.20.10	Mainly Alpha	Up-down Bundle	F1FO ATP Synthase	F1F0 ATP synthase subunit C	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
AA [auth X]	PF00119	ATP synthase A chain (ATP-synt_A)	ATP synthase A chain	-	Domain
CA [auth Z]	PF07345	ATPase inhibitor subunit zeta (ATPaseInh_sub_z)	ATPase inhibitor subunit zeta	This entry represents zeta-subunits, which are found in alpha-proteobacterial F1F0-ATPase regulatory proteins. The zeta subunit is a potent inhibitor of the alpha-proteobacterial F1FO-ATPase. The inhibitory region resides in the first 14 N-terminal r ...	This entry represents zeta-subunits, which are found in alpha-proteobacterial F1F0-ATPase regulatory proteins. The zeta subunit is a potent inhibitor of the alpha-proteobacterial F1FO-ATPase. The inhibitory region resides in the first 14 N-terminal residues of the protein, which protrude from the 4-alpha-helix bundle structure of the isolated zeta subunit [1, 2, 3].	Domain
D [auth A], E [auth B], F [auth C]	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain (ATP-synt_ab)	ATP synthase alpha/beta family, nucleotide-binding domain	This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.	Domain
D [auth A], E [auth B], F [auth C]	PF00306	ATP synthase alpha/beta chain, C terminal domain (ATP-synt_ab_C)	ATP synthase alpha/beta chain, C terminal domain	-	Domain
D [auth A], E [auth B], F [auth C]	PF02874	ATP synthase alpha/beta family, beta-barrel domain (ATP-synt_ab_N)	ATP synthase alpha/beta family, beta-barrel domain	This family includes the ATP synthase alpha and beta subunits the ATP synthase associated with flagella.	Domain
G [auth D], H [auth E], I [auth F]	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain (ATP-synt_ab)	ATP synthase alpha/beta family, nucleotide-binding domain	This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.	Domain
G [auth D], H [auth E], I [auth F]	PF02874	ATP synthase alpha/beta family, beta-barrel domain (ATP-synt_ab_N)	ATP synthase alpha/beta family, beta-barrel domain	This family includes the ATP synthase alpha and beta subunits the ATP synthase associated with flagella.	Domain
J [auth G]	PF00231	ATP synthase (ATP-synt)	ATP synthase	-	Domain
K [auth H]	PF00213	ATP synthase delta (OSCP) subunit (OSCP)	ATP synthase delta (OSCP) subunit	-	Family
L [auth I]	PF02823	ATP synthase, Delta/Epsilon chain, beta-sandwich domain (ATP-synt_DE_N)	ATP synthase, Delta/Epsilon chain, beta-sandwich domain	Part of the ATP synthase CF(1). These subunits are part of the head unit of the ATP synthase. The subunit is called epsilon in bacteria and delta in mitochondria. In bacteria the delta (D) subunit is equivalent to the mitochondrial Oligomycin sensit ...	Part of the ATP synthase CF(1). These subunits are part of the head unit of the ATP synthase. The subunit is called epsilon in bacteria and delta in mitochondria. In bacteria the delta (D) subunit is equivalent to the mitochondrial Oligomycin sensitive subunit, OSCP (Pfam:PF00213).	Domain
M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], R [auth O], S [auth P], T [auth Q], U [auth R], V [auth S], W [auth T], X [auth U]	PF00137	ATP synthase subunit C (ATP-synt_C)	ATP synthase subunit C	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth 1]	Chain A	-	-	-
Y [auth V]	Chain V	-	-	-
Z [auth W]	Chain W	-	-	-
AA [auth X]	ATP synthase subunit a,ATP synthase subunit a,ATP synthase subunit a,ATP synthase subunit a	monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity ligase activity	-	cell periphery plasma membrane membrane cellular anatomical entity protein-containing complex ATPase complex intracellular anatomical structure catalytic complex proton-transporting ATP synthase complex membrane protein complex proton-transporting two-sector ATPase complex, proton-transporting domain proton-transporting two-sector ATPase complex proton-transporting ATP synthase complex, coupling factor F(o)
BA [auth Y]	Chain Y	-	-	-
CA [auth Z]	Zeta inhibitor protein	molecular function inhibitor activity molecular function regulator activity	-	-
B [auth 2]	Chain B	-	-	-
C [auth 3]	Chain C	-	-	-
D [auth A], E [auth B], F [auth C]	ATP synthase subunit alpha	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding monoatomic cation transmembrane transporter activity proton transmembrane transporter activity primary active transmembrane transporter activity ATPase-coupled transmembrane transporter activity proton-transporting ATPase activity, rotational mechanism ATPase-coupled monoatomic cation transmembrane transporter activity ATP-dependent activity active monoatomic ion transmembrane transporter activity ATPase-coupled ion transmembrane transporter activity active transmembrane transporter activity ATPase activity, coupled to transmembrane movement of ions, rotational mechanism inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity channel activity catalytic activity ligase activity	-	protein-containing complex ATPase complex intracellular anatomical structure catalytic complex proton-transporting ATP synthase complex membrane membrane protein complex cellular anatomical entity proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) cell periphery plasma membrane
G [auth D], H [auth E], I [auth F]	ATP synthase subunit beta	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding monoatomic cation transmembrane transporter activity proton transmembrane transporter activity primary active transmembrane transporter activity ATPase-coupled transmembrane transporter activity proton-transporting ATPase activity, rotational mechanism ATPase-coupled monoatomic cation transmembrane transporter activity ATP-dependent activity active monoatomic ion transmembrane transporter activity ATPase-coupled ion transmembrane transporter activity active transmembrane transporter activity ATPase activity, coupled to transmembrane movement of ions, rotational mechanism inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity channel activity ligase activity	-	protein-containing complex ATPase complex intracellular anatomical structure catalytic complex proton-transporting ATP synthase complex membrane membrane protein complex cellular anatomical entity proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) cell periphery plasma membrane
J [auth G]	ATP synthase gamma chain	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity ligase activity	nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleoside triphosphate biosynthetic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process phosphorus metabolic process ribose phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleoside triphosphate biosynthetic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process phosphorus metabolic process ribose phosphate biosynthetic process nucleoside phosphate metabolic process proton motive force-driven plasma membrane ATP synthesis cellular metabolic process primary metabolic process nucleotide metabolic process ribonucleoside triphosphate biosynthetic process organic cyclic compound metabolic process biosynthetic process organophosphate biosynthetic process organic cyclic compound biosynthetic process nucleoside phosphate biosynthetic process metabolic process nucleoside triphosphate metabolic process purine ribonucleotide metabolic process purine nucleotide biosynthetic process ribose phosphate metabolic process ATP metabolic process ATP biosynthetic process proton motive force-driven ATP synthesis purine nucleotide metabolic process organic substance metabolic process ribonucleotide metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process purine ribonucleoside triphosphate metabolic process ribonucleoside triphosphate metabolic process carbohydrate derivative biosynthetic process purine nucleoside triphosphate metabolic process organonitrogen compound metabolic process nucleoside triphosphate biosynthetic process nucleobase-containing compound biosynthetic process purine-containing compound metabolic process organophosphate metabolic process cellular process	protein-containing complex ATPase complex intracellular anatomical structure catalytic complex proton-transporting ATP synthase complex membrane membrane protein complex cellular anatomical entity proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) cell periphery plasma membrane
K [auth H]	ATP synthase subunit delta	monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity ligase activity	-	protein-containing complex ATPase complex intracellular anatomical structure catalytic complex proton-transporting ATP synthase complex membrane membrane protein complex cellular anatomical entity proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) cell periphery plasma membrane
L [auth I]	ATP synthase epsilon chain	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity ligase activity	-	protein-containing complex ATPase complex intracellular anatomical structure catalytic complex proton-transporting ATP synthase complex membrane membrane protein complex cellular anatomical entity proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) cell periphery plasma membrane
M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], R [auth O], S [auth P], T [auth Q], U [auth R], V [auth S], W [auth T], X [auth U]	ATP synthase F0 subcomplex C subunit	binding lipid binding monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity binding lipid binding monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity ligase activity	-	cell periphery plasma membrane membrane cellular anatomical entity membrane-bounded organelle intracellular organelle intracellular anatomical structure organelle intracellular membrane-bounded organelle cytoplasm protein-containing complex ATPase complex catalytic complex proton-transporting ATP synthase complex cell periphery plasma membrane membrane cellular anatomical entity membrane-bounded organelle intracellular organelle intracellular anatomical structure organelle intracellular membrane-bounded organelle cytoplasm protein-containing complex ATPase complex catalytic complex proton-transporting ATP synthase complex membrane protein complex proton-transporting two-sector ATPase complex, proton-transporting domain proton-transporting two-sector ATPase complex proton-transporting ATP synthase complex, coupling factor F(o)

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
AA [auth X]	IPR023011	ATP synthase, F0 complex, subunit A, active site	Active Site
AA [auth X]	IPR000568	ATP synthase, F0 complex, subunit A	Family
AA [auth X]	IPR035908	ATP synthase, F0 complex, subunit A superfamily	Homologous Superfamily
AA [auth X]	IPR045083	ATP synthase, F0 complex, subunit A, bacterial/mitochondria	Family
CA [auth Z]	IPR038293	ATPase inhibitor subunit zeta superfamily	Homologous Superfamily
CA [auth Z]	IPR009945	ATPase inhibitor subunit zeta	Family
D [auth A], E [auth B], F [auth C]	IPR038376	ATP synthase, alpha subunit, C-terminal domain superfamily	Homologous Superfamily
D [auth A], E [auth B], F [auth C]	IPR004100	ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain	Domain
D [auth A], E [auth B], F [auth C]	IPR033732	ATP synthase, F1 complex, alpha subunit nucleotide-binding domain	Domain
D [auth A], E [auth B], F [auth C]	IPR036121	ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily	Homologous Superfamily
D [auth A], E [auth B], F [auth C]	IPR023366	ATP synthase subunit alpha, N-terminal domain-like superfamily	Homologous Superfamily
D [auth A], E [auth B], F [auth C]	IPR000793	ATP synthase, alpha subunit, C-terminal	Domain
D [auth A], E [auth B], F [auth C]	IPR020003	ATPase, alpha/beta subunit, nucleotide-binding domain, active site	Active Site
D [auth A], E [auth B], F [auth C]	IPR000194	ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain	Domain
D [auth A], E [auth B], F [auth C]	IPR005294	ATP synthase, F1 complex, alpha subunit	Family
D [auth A], E [auth B], F [auth C]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
G [auth D], H [auth E], I [auth F]	IPR004100	ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain	Domain
G [auth D], H [auth E], I [auth F]	IPR024034	ATPase, F1/V1 complex, beta/alpha subunit, C-terminal	Homologous Superfamily
G [auth D], H [auth E], I [auth F]	IPR036121	ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily	Homologous Superfamily
G [auth D], H [auth E], I [auth F]	IPR020003	ATPase, alpha/beta subunit, nucleotide-binding domain, active site	Active Site
G [auth D], H [auth E], I [auth F]	IPR000194	ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain	Domain
G [auth D], H [auth E], I [auth F]	IPR003593	AAA+ ATPase domain	Domain
G [auth D], H [auth E], I [auth F]	IPR005722	ATP synthase, F1 complex, beta subunit	Family
G [auth D], H [auth E], I [auth F]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
J [auth G]	IPR023632	ATP synthase, F1 complex, gamma subunit conserved site	Conserved Site
J [auth G]	IPR000131	ATP synthase, F1 complex, gamma subunit	Family
J [auth G]	IPR035968	ATP synthase, F1 complex, gamma subunit superfamily	Homologous Superfamily
K [auth H]	IPR020781	ATPase, OSCP/delta subunit, conserved site	Conserved Site
K [auth H]	IPR000711	ATPase, OSCP/delta subunit	Family
K [auth H]	IPR026015	F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily	Homologous Superfamily
L [auth I]	IPR036771	F0F1 ATP synthase delta/epsilon subunit, N-terminal	Homologous Superfamily
L [auth I]	IPR020546	ATP synthase, F1 complex, delta/epsilon subunit, N-terminal	Domain
L [auth I]	IPR001469	ATP synthase, F1 complex, delta/epsilon subunit	Family
M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], R [auth O], S [auth P], T [auth Q], U [auth R], V [auth S], W [auth T], X [auth U]	IPR035921	F/V-ATP synthase subunit C superfamily	Homologous Superfamily
M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], R [auth O], S [auth P], T [auth Q], U [auth R], V [auth S], W [auth T], X [auth U]	IPR038662	F1F0 ATP synthase subunit C superfamily	Homologous Superfamily
M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], R [auth O], S [auth P], T [auth Q], U [auth R], V [auth S], W [auth T], X [auth U]	IPR000454	ATP synthase, F0 complex, subunit C	Family
M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], R [auth O], S [auth P], T [auth Q], U [auth R], V [auth S], W [auth T], X [auth U]	IPR002379	V-ATPase proteolipid subunit C-like domain	Domain

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
AA [auth X], D [auth A], E [auth B], F [auth C], G [auth D] AA [auth X], D [auth A], E [auth B], F [auth C], G [auth D], H [auth E], I [auth F], J [auth G], K [auth H], L [auth I], M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], R [auth O], S [auth P], T [auth Q], U [auth R], V [auth S], W [auth T], X [auth U]	OPM	Transmembrane	Alpha-helical polytopic	Proton or Sodium translocating F-type, V-type and A-type ATPases	V-type and F-type ATPases

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
AA [auth X], D [auth A], E [auth B], F [auth C], G [auth D] AA [auth X], D [auth A], E [auth B], F [auth C], G [auth D], H [auth E], I [auth F], J [auth G], K [auth H], L [auth I], M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], R [auth O], S [auth P], T [auth Q], U [auth R], V [auth S], W [auth T], X [auth U]	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
AA [auth X], D [auth A], E [auth B], F [auth C], G [auth D] AA [auth X], D [auth A], E [auth B], F [auth C], G [auth D], H [auth E], I [auth F], J [auth G], K [auth H], L [auth I], M [auth J], N [auth K], O [auth L], P [auth M], Q [auth N], R [auth O], S [auth P], T [auth Q], U [auth R], V [auth S], W [auth T], X [auth U]	MemProtMD	Annotated as membrane protein by MemProtMD