4GSL
Crystal structure of an Atg7-Atg3 crosslinked complex
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | JAB1/MPN domain-like | 8052657 | 3001105 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | JAB1/MPN domain-like | 8052658 | 3001105 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | JAB1/MPN domain-like | 8052658 | 3001105 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | JAB1/MPN domain-like | 8052657 | 3001105 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00899 | e4gslA1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: Activating enzymes of the ubiquitin-like proteins | F: PF00899 | ECOD (1.6) |
A | F_UNCLASSIFIED | e4gslA3 | A: a/b three-layered sandwiches | X: Atg7 N-terminal domain-like | H: N-terminal domain in E1 enzyme Atg7 (From Topology) | T: N-terminal domain in E1 enzyme Atg7 | F: F_UNCLASSIFIED | ECOD (1.6) |
A | PF16420 | e4gslA2 | A: a/b three-layered sandwiches | X: Atg7 N-terminal domain-like | H: N-terminal domain in E1 enzyme Atg7 (From Topology) | T: N-terminal domain in E1 enzyme Atg7 | F: PF16420 | ECOD (1.6) |
B | PF00899 | e4gslB1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: Activating enzymes of the ubiquitin-like proteins | F: PF00899 | ECOD (1.6) |
B | F_UNCLASSIFIED | e4gslB3 | A: a/b three-layered sandwiches | X: Atg7 N-terminal domain-like | H: N-terminal domain in E1 enzyme Atg7 (From Topology) | T: N-terminal domain in E1 enzyme Atg7 | F: F_UNCLASSIFIED | ECOD (1.6) |
B | PF16420 | e4gslB2 | A: a/b three-layered sandwiches | X: Atg7 N-terminal domain-like | H: N-terminal domain in E1 enzyme Atg7 (From Topology) | T: N-terminal domain in E1 enzyme Atg7 | F: PF16420 | ECOD (1.6) |
C | PF03987 | e4gslC2 | A: a+b two layers | X: UBC-like | H: UBC-like (From Topology) | T: UBC-like | F: PF03987 | ECOD (1.6) |
D | PF03987 | e4gslD2 | A: a+b two layers | X: UBC-like | H: UBC-like (From Topology) | T: UBC-like | F: PF03987 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.720 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain | CATH (4.3.0) |
B | 3.40.50.720 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00899 | ThiF family (ThiF) | ThiF family | This domain is found in ubiquitin activating E1 family and members of the bacterial ThiF/MoeB/HesA family. It is repeated in Ubiquitin-activating enzyme E1 [1-3]. | Domain | |
PF16420 | Ubiquitin-like modifier-activating enzyme ATG7 N-terminus (ATG7_N) | Ubiquitin-like modifier-activating enzyme ATG7 N-terminus | This is the N-terminal domain of Ubiquitin-like modifier-activating enzyme ATG7. In Arabidopsis this domain binds the E2 enzymes ATG10 and ATG3 [1]. | Domain | |
PF03987 | Autophagocytosis associated protein, active-site domain (Autophagy_act_C) | Autophagocytosis associated protein, active-site domain | Autophagocytosis is a starvation-induced process responsible for transport of cytoplasmic proteins to the vacuole. The cysteine residue within the HPC motif is the putative active-site residue for recognition of the Apg5 subunit of the autophagosome ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR045886 | ThiF/MoeB/HesA family | Family | |
IPR006285 | Ubiquitin-like modifier-activating enzyme Atg7 | Family | |
IPR042522 | Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 | Homologous Superfamily | |
IPR000594 | THIF-type NAD/FAD binding fold | Domain | |
IPR032197 | Ubiquitin-like modifier-activating enzyme Atg7, N-terminal | Domain | |
IPR042523 | Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 | Homologous Superfamily | |
IPR035985 | Ubiquitin-activating enzyme | Homologous Superfamily | |
IPR007135 | Ubiquitin-like-conjugating enzyme Atg3/Atg10 | Family | |
IPR046962 | Autophagy-related protein 3 | Family |