4FW2
Crystal structure of RSV three-domain integrase with disordered N-terminal domain
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d4fw2a2 | All beta proteins | SH3-like barrel | DNA-binding domain of retroviral integrase | automated matches | automated matches | RSV-PrC (Rous sarcoma virus - Prague C ) [TaxId: 11888 ], | SCOPe (2.08) |
A | d4fw2a1 | Alpha and beta proteins (a/b) | Ribonuclease H-like motif | Ribonuclease H-like | Retroviral integrase, catalytic domain | automated matches | RSV-PrC (Rous sarcoma virus - Prague C ) [TaxId: 11888 ], | SCOPe (2.08) |
B | d4fw2b2 | All beta proteins | SH3-like barrel | DNA-binding domain of retroviral integrase | automated matches | automated matches | RSV-PrC (Rous sarcoma virus - Prague C ) [TaxId: 11888 ], | SCOPe (2.08) |
B | d4fw2b1 | Alpha and beta proteins (a/b) | Ribonuclease H-like motif | Ribonuclease H-like | Retroviral integrase, catalytic domain | automated matches | RSV-PrC (Rous sarcoma virus - Prague C ) [TaxId: 11888 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00552 | e4fw2A1 | A: beta barrels | X: SH3 | H: SH3 | T: SH3 | F: PF00552 | ECOD (1.6) |
A | PF00665 | e4fw2A2 | A: mixed a+b and a/b | X: Ribonuclease H-like | H: Ribonuclease H-like (From Topology) | T: Ribonuclease H-like | F: PF00665 | ECOD (1.6) |
B | PF00552 | e4fw2B1 | A: beta barrels | X: SH3 | H: SH3 | T: SH3 | F: PF00552 | ECOD (1.6) |
B | PF00665 | e4fw2B2 | A: mixed a+b and a/b | X: Ribonuclease H-like | H: Ribonuclease H-like (From Topology) | T: Ribonuclease H-like | F: PF00665 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.30.420.10 | Alpha Beta | 2-Layer Sandwich | Nucleotidyltransferase | domain 5 | CATH (4.3.0) |
A | 2.30.30.10 | Mainly Beta | Roll | SH3 type barrels. | Integrase, C-terminal domain superfamily, retroviral | CATH (4.3.0) |
B | 3.30.420.10 | Alpha Beta | 2-Layer Sandwich | Nucleotidyltransferase | domain 5 | CATH (4.3.0) |
B | 2.30.30.10 | Mainly Beta | Roll | SH3 type barrels. | Integrase, C-terminal domain superfamily, retroviral | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00552 | Integrase DNA binding domain (IN_DBD_C) | Integrase DNA binding domain | Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain. The central domain is the catalytic domain Pfam:PF00665. This do ... | Domain |