Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AEndotoxin_Ce4d8mA1 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Endotoxin_CECOD (1.6)
AEUF07870e4d8mA7 A: beta duplicates or obligate multimersX: beta-Prism I (From Topology)H: beta-Prism I (From Topology)T: beta-Prism IF: EUF07870ECOD (1.6)
AEndotoxin_Ne4d8mA6 A: alpha arraysX: Toxins' membrane translocation domainsH: delta-Endotoxin (insectocide), N-terminal domain (From Topology)T: delta-Endotoxin (insectocide), N-terminal domainF: Endotoxin_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A1.20.190.10 Mainly Alpha Up-down Bundle Delta-Endotoxin domain 1CATH (4.3.0)
A2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-likeCATH (4.3.0)
A2.100.10.40 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF03944delta endotoxin (Endotoxin_C)delta endotoxinThis family contains insecticidal toxins produced by Bacillus species of bacteria. During spore formation the bacteria produce crystals of this protein. When an insect ingests these proteins they are activated by proteolytic cleavage. The N termin ...This family contains insecticidal toxins produced by Bacillus species of bacteria. During spore formation the bacteria produce crystals of this protein. When an insect ingests these proteins they are activated by proteolytic cleavage. The N terminus is cleaved in all of the proteins and a C terminal extension is cleaved in some members. Once activated the endotoxin binds to the gut epithelium and causes cell lysis leading to death. This activated region of the delta endotoxin is composed of three structural domains. The N-terminal helical domain is involved in membrane insertion and pore formation. The second and third domains are involved in receptor binding.
Domain
PF03945delta endotoxin, N-terminal domain (Endotoxin_N)delta endotoxin, N-terminal domainThis family contains insecticidal toxins produced by Bacillus species of bacteria. During spore formation the bacteria produce crystals of this protein. When an insect ingests these proteins they are activated by proteolytic cleavage. The N termin ...This family contains insecticidal toxins produced by Bacillus species of bacteria. During spore formation the bacteria produce crystals of this protein. When an insect ingests these proteins they are activated by proteolytic cleavage. The N terminus is cleaved in all of the proteins and a C terminal extension is cleaved in some members. Once activated the endotoxin binds to the gut epithelium and causes cell lysis leading to death. This activated region of the delta endotoxin is composed of three structural domains. The N-terminal helical domain is involved in membrane insertion and pore formation. The second and third domains are involved in receptor binding.
Domain