Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ALRR_8_3e3rizA1 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: LRR_8_3ECOD (1.6)
ALRR_8_2e3rizA2 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: LRR_8_2ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease InhibitorCATH (4.3.0)
A3.30.1490.310 Alpha Beta 2-Layer Sandwich Dna Ligase domain 1CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF13855Leucine rich repeat (LRR_8)Leucine rich repeat- Repeat
PF08263Leucine rich repeat N-terminal domain (LRRNT_2)Leucine rich repeat N-terminal domain- Family
PF20141Brassinosteroid receptor island domain (Island)Brassinosteroid receptor island domainThe island domain in BRI1 corresponds to a large insertion in the regular repeat-structure between LRRs 21 and 22. The resulting 70-residue segment forms a small domain that folds back into the interior of the LRR superhelix, where it makes extensive ...The island domain in BRI1 corresponds to a large insertion in the regular repeat-structure between LRRs 21 and 22. The resulting 70-residue segment forms a small domain that folds back into the interior of the LRR superhelix, where it makes extensive polar and hydrophobic interactions with LRRs 13-25. The domain fold is characterized by an anti-parallel beta-sheet, which is sandwiched between the LRR core and a 3-10 helix and stabilized by a disulphide bridge. The insertion of a folded domain into the LRR repeat has not been observed in other LRR receptor structures, and is probably an adaptation to the challenge of sensing a small steroid ligand (rather than larger ligands, such as proteins, nucleic acids, or lipids.
Domain
PF00560Leucine Rich Repeat (LRR_1)Leucine Rich Repeat- Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Protein BRASSINOSTEROID INSENSITIVE 1