Annotations: 3E76

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C	PF00118	e3e76C1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
C	PF00118	e3e76C3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
C	F_UNCLASSIFIED	e3e76C2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
J	PF00118	e3e76J1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
J	PF00118	e3e76J3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
J	F_UNCLASSIFIED	e3e76J2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
K	PF00118	e3e76K1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
K	PF00118	e3e76K3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
K	F_UNCLASSIFIED	e3e76K2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
L	PF00118	e3e76L1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
L	PF00118	e3e76L3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
L	F_UNCLASSIFIED	e3e76L2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
N	PF00118	e3e76N1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
N	PF00118	e3e76N3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
N	F_UNCLASSIFIED	e3e76N2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF00118	e3e76A1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
A	PF00118	e3e76A3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
A	F_UNCLASSIFIED	e3e76A2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF00118	e3e76B1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
B	PF00118	e3e76B3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
B	F_UNCLASSIFIED	e3e76B2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
D	PF00118	e3e76D1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
D	PF00118	e3e76D3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
D	F_UNCLASSIFIED	e3e76D2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
E	PF00118	e3e76E1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
E	PF00118	e3e76E3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
E	F_UNCLASSIFIED	e3e76E2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
F	PF00118	e3e76F1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
F	PF00118	e3e76F3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
F	F_UNCLASSIFIED	e3e76F2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
G	PF00118	e3e76G1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
G	PF00118	e3e76G3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
G	F_UNCLASSIFIED	e3e76G2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
H	PF00118	e3e76H1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
H	PF00118	e3e76H3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
H	F_UNCLASSIFIED	e3e76H2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
I	PF00118	e3e76I1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
I	PF00118	e3e76I3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
I	F_UNCLASSIFIED	e3e76I2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
M	PF00118	e3e76M1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
M	PF00118	e3e76M3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
M	F_UNCLASSIFIED	e3e76M2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
C	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
C	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
J	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
J	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
J	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
K	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
K	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
K	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
L	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
L	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
L	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
N	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
N	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
N	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
A	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
A	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
A	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
B	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
B	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
B	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
D	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
D	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
D	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
E	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
E	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
E	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
F	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
F	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
F	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
G	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
G	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
G	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
H	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
H	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
H	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
I	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
I	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
I	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
M	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
M	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
M	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	60 kDa chaperonin	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding isomerase activity catalytic activity unfolded protein binding protein binding ATP-dependent protein folding chaperone protein folding chaperone ATP-dependent activity	protein refolding organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein refolding organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR018370	Chaperonin Cpn60, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR001844	Chaperonin Cpn60/GroEL	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family