5M02

Crystal structure of murine P14 TCR / H-2Db with PF, modified gp33 peptide from LCMV


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.75 Å
  • R-Value Free: 0.214 
  • R-Value Work: 0.188 
  • R-Value Observed: 0.189 

wwPDB Validation   3D Report Full Report


This is version 1.1 of the entry. See complete history


Literature

Thernary complexes of TCR P14 give insights into the mechanisms behind reestablishment of CTL responses against a viral escape mutant

Allerbring, E.Duru, A.Sun, R.Han, X.Uchtenhagen, H.Madhurantakam, C.Popov, A.Markova, N.Talyzina, A.Nygren, P.A.Sandalova, T.Achour, A.

To be published.

Macromolecules
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Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
H-2 class I histocompatibility antigen, D-B alpha chain276Mus musculusMutation(s): 0 
Gene Names: H2-D1
UniProt
Find proteins for P01899 (Mus musculus)
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UniProt GroupP01899
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Entity ID: 2
MoleculeChains Sequence LengthOrganismDetailsImage
Beta-2-microglobulin119Mus musculusMutation(s): 1 
Gene Names: B2m
UniProt & NIH Common Fund Data Resources
Find proteins for P01887 (Mus musculus)
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IMPC:  MGI:88127
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UniProt GroupP01887
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Entity ID: 3
MoleculeChains Sequence LengthOrganismDetailsImage
Protein Trav14-1,T-cell receptor alpha chain C regionC [auth G]205Mus musculusMutation(s): 0 
Gene Names: Trav14-1Tcra
UniProt
Find proteins for P01849 (Mus musculus)
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Find proteins for A0A0G2JF94 (Mus musculus)
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UniProt GroupsA0A0G2JF94P01849
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Entity ID: 4
MoleculeChains Sequence LengthOrganismDetailsImage
T-cell receptor beta chain V region C5,T-cell receptor beta-2 chain C regionD [auth H]238Mus musculusMutation(s): 0 
UniProt
Find proteins for P04213 (Mus musculus)
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Find proteins for P01851 (Mus musculus)
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UniProt GroupsP04213P01851
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Entity ID: 5
MoleculeChains Sequence LengthOrganismDetailsImage
LCMV-DERIVED GP33 ALTERED PEPTIDE LIGAND PFE [auth P]9Mammarenavirus choriomeningitidisMutation(s): 0 
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.75 Å
  • R-Value Free: 0.214 
  • R-Value Work: 0.188 
  • R-Value Observed: 0.189 
  • Space Group: C 1 2 1
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 255.11α = 90
b = 46.5β = 94.6
c = 89.02γ = 90
Software Package:
Software NamePurpose
REFMACrefinement
XDSdata reduction
Aimlessdata scaling
PHASERphasing

Structure Validation

View Full Validation Report



Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 2017-12-20
    Type: Initial release
  • Version 1.1: 2024-01-17
    Changes: Data collection, Database references, Refinement description