3V2W
Crystal Structure of a Lipid G protein-Coupled Receptor at 3.35A
- PDB DOI: https://doi.org/10.2210/pdb3V2W/pdb
- Classification: HYDROLASE
- Organism(s): Homo sapiens, Tequatrovirus T4
- Expression System: Spodoptera frugiperda
- Mutation(s): Yes 
- Membrane Protein: Yes  PDBTMMemProtMDmpstruc
- Deposited: 2011-12-12 Released: 2012-02-15 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 3.35 Å
- R-Value Free: 0.281 
- R-Value Work: 0.224 
- R-Value Observed: 0.228 
This is version 1.4 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Sphingosine 1-phosphate receptor 1, Lysozyme chimera | 520 | Homo sapiens, Tequatrovirus T4 | Mutation(s): 2  Gene Names: S1PR1, CHEDG1, EDG1 EC: 3.2.1.17 Membrane Entity: Yes  | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P21453 (Homo sapiens) Explore P21453  Go to UniProtKB:  P21453 | |||||
PHAROS:  P21453 GTEx:  ENSG00000170989  | |||||
Find proteins for P00720 (Enterobacteria phage T4) Explore P00720  Go to UniProtKB:  P00720 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Groups | P00720P21453 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
Ligands 2 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
ML5 Query on ML5 | B [auth A] | {(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl}phosphonic acid C16 H27 N2 O4 P FWJRVGZWNDOOFH-OAHLLOKOSA-N | |||
NAG Query on NAG | C [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 3.35 Å
- R-Value Free: 0.281 
- R-Value Work: 0.224 
- R-Value Observed: 0.228 
- Space Group: P 21 21 2
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 107.94 | α = 90 |
b = 69.7 | β = 90 |
c = 81.93 | γ = 90 |
Software Name | Purpose |
---|---|
PHASER | phasing |
BUSTER | refinement |
XDS | data reduction |
XDS | data scaling |
Entry History 
Deposition Data
- Released Date: 2012-02-15  Deposition Author(s): Hanson, M.A., Roth, C.B., Jo, E., Griffith, M.T., Scott, F.L., Reinhart, G., Desale, H., Clemons, B., Cahalan, S.M., Schuerer, S.C., Sanna, M.G., Han, G.W., Kuhn, P., Rosen, H., Stevens, R.C., GPCR Network (GPCR)
Revision History (Full details and data files)
- Version 1.0: 2012-02-15
Type: Initial release - Version 1.1: 2012-03-14
Changes: Database references - Version 1.2: 2017-06-21
Changes: Data collection, Database references, Source and taxonomy, Structure summary - Version 1.3: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Derived calculations, Structure summary - Version 1.4: 2024-04-03
Changes: Data collection, Database references, Refinement description, Structure summary