LLP

(2S)-2-amino-6-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]hexanoic acid



Chemical Component Summary

Name(2S)-2-amino-6-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]hexanoic acid
SynonymsN'-PYRIDOXYL-LYSINE-5'-MONOPHOSPHATE
Identifiers2-azanyl-6-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]hexanoic acid
FormulaC14 H22 N3 O7 P
Molecular Weight375.314
TypeL-PEPTIDE LINKING
Isomeric SMILESCc1c(c(c(cn1)COP(=O)(O)O)/C=N/CCCCC(C(=O)O)N)O
InChIInChI=1S/C14H22N3O7P/c1-9-13(18)11(10(6-17-9)8-24-25(21,22)23)7-16-5-3-2-4-12(15)14(19)20/h6-7,12,18H,2-5,8,15H2,1H3,(H,19,20)(H2,21,22,23)/b16-7+/t12-/m0/s1
InChIKeyYQSOQJORMNSDJL-QFULYMJESA-N

Chemical Details

Formal Charge0
Atom Count47
Chiral Atom Count1
Bond Count47
Aromatic Bond Count6

Drug Info: DrugBank

DrugBank IDDB04083 
NameN(6)-(pyridoxal phosphate)-L-lysine
Groups experimental
Synonyms
  • N6-((3-Hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methylene)-L-lysine
  • (S)-2-amino-6-[(3-hydroxy-2-methyl-5-phosphonooxymethyl-4-pyridine)methyleneamino]hexanoic acid
  • N(6)-(pyridoxal phosphate)-L-lysine
CAS number2440-59-7

Drug Targets

NameTarget SequencePharmacological ActionActions
Kynurenine--oxoglutarate transaminase 1MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAF...unknown
Ornithine decarboxylaseMNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILK...unknown
Adenosylmethionine-8-amino-7-oxononanoate aminotransferaseMTTDDLAFDQRHIWHPYTSMTSPLPVYPVVSAEGCELILSDGRRLVDGMS...unknown
Glycogen phosphorylase, muscle formMSRPLSDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPR...unknown
Serine--pyruvate aminotransferaseMASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMS...unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682