Chemical Component Summary

NamePHENOL
Identifiersphenol
FormulaC6 H6 O
Molecular Weight94.111
TypeNON-POLYMER
Isomeric SMILESc1ccc(cc1)O
InChIInChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H
InChIKeyISWSIDIOOBJBQZ-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count13
Chiral Atom Count0
Bond Count13
Aromatic Bond Count6

Drug Info: DrugBank

DrugBank IDDB03255 
NamePhenol
Groups
  • experimental
  • approved
DescriptionPhenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products such as Chloraseptic to treat pharyngitis. Additionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process termed phenolization. Research indicates that parental exposure to phenol and its related compounds are positively associated with spontaneous abortion. During the second world war, phenol injections were used as a means of execution by the Nazis. Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract.
Synonyms
  • Carbolic acid
  • Acide carbolique
  • Oxybenzene
  • Benzenol
  • Phenyl alcohol
Brand Names
  • Premier Value Instant Antiseptic Pain Relief
  • Blistex Lip
  • Liver supplement
  • DDM Instant Antiseptic Pain Relief
  • Carmex Lip Ointment
IndicationPhenol is primarily indicated for minor sore throat pain, sore mouth, minor mouth irritation, and pain associated with canker sores. Additionally, phenol is indicated in the treatment of focal spasticity.
Categories
  • Anesthetics
  • Anesthetics, Local
  • Anti-Infective Agents
  • Anti-Infective Agents, Local
  • Antiseptics and Disinfectants
ATC-Code
  • C05BB05
  • R02AA19
  • N01BX03
  • D08AE03
CAS number108-95-2

Drug Targets

NameTarget SequencePharmacological ActionActions
Serum albuminMKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...unknown
ThermolysinMKMKMKLASFGLAAGLAAQVFLPYNALASTEHVTWNQQFQTPQFISGDLL...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 20488062, 996
ChEMBL CHEMBL14060
ChEBI CHEBI:15882
CCDC/CSD AGOKEN, JIMRON, DEVXOS, JUCYAH, AGOTEV, DIKSAS, FOTBAR, FOTBAR10, JECJAC, EBILOR, LAWWOW, EREKAN, JECHUU, LUNCAB, GOKPAA, CAFVOW, FAJYOF, GOKPAA01, HIBFON, FINPUN, HIBFED, DILSOI, ISEKAS, OLAQAT, MARCIT, BOPDAO, LASXUY, HIBFIH, LODLIB, FORQUB, MITGEB, MPPZPO, GIXNOQ, COHWOL, CUXMOA, KACKOS, AZEZEN
COD 2103472