6MET
Structural basis of coreceptor recognition by HIV-1 envelope spike
External Resource: Annotation
- Domain Annotation: SCOP2 Classification
- Domain Annotation: ECOD Classification
- Protein Family Annotation
- Gene Ontology: Gene Product Annotation
- InterPro: Protein Family Classification
- Pharos: Disease Associations
- Membrane Protein Annotation: PDBTM
- Membrane Protein Annotation: MemProtMD
- Protein Modification Annotation
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B [auth A] | SCOP2B Superfamily | Immunoglobulin (Ig) domain-like | 8054739 | 3000071 | SCOP2B (2022-06-29) |
B [auth A] | SCOP2B Superfamily | Immunoglobulin (Ig) domain-like | 8054493 | 3000071 | SCOP2B (2022-06-29) |
A [auth G] | SCOP2B Superfamily | gp120 core | 8099868 | 3001390 | SCOP2B (2022-06-29) |
C [auth B] | SCOP2B Superfamily | G protein-coupled receptor-like | 8091224 | 3000473 | SCOP2B (2022-06-29) |
C [auth B] | SCOP2B Superfamily | G protein-coupled receptor-like | 8091224 | 3000473 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B [auth A] | PF00047 | e6metA1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF00047 | ECOD (1.6) |
B [auth A] | PF05790 | e6metA2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF05790 | ECOD (1.6) |
B [auth A] | PF09191 | e6metA4 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF09191 | ECOD (1.6) |
A [auth G] | F_UNCLASSIFIED | e6metG2 | A: beta barrels | X: V1/V2 domain in HIV gp120 (From Topology) | H: V1/V2 domain in HIV gp120 (From Topology) | T: V1/V2 domain in HIV gp120 | F: F_UNCLASSIFIED | ECOD (1.6) |
A [auth G] | PF00516 | e6metG1 | A: a+b two layers | X: Ribosomal protein L31e-like | H: Ribosomal protein L31e/gp120 outer domain (From Topology) | T: Ribosomal protein L31e/gp120 outer domain | F: PF00516 | ECOD (1.6) |
A [auth G] | PF00516 | e6metG3 | A: a+b two layers | X: gp120 inner domain (From Topology) | H: gp120 inner domain (From Topology) | T: gp120 inner domain | F: PF00516 | ECOD (1.6) |
C [auth B] | PF00001 | e6metB1 | A: alpha bundles | X: Family A G protein-coupled receptor-like (From Topology) | H: Family A G protein-coupled receptor-like (From Topology) | T: Family A G protein-coupled receptor-like | F: PF00001 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
B [auth A] | PF05790 | Immunoglobulin C2-set domain (C2-set) | Immunoglobulin C2-set domain | - | Domain |
B [auth A] | PF00047 | Immunoglobulin domain (ig) | Immunoglobulin domain | Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions. Examples include antibodies, the giant muscle kinase titin and receptor tyrosine kinases. Immunoglobulin-like domains may be involved in protein-prot ... | Domain |
B [auth A] | PF09191 | CD4, extracellular (CD4-extracel) | CD4, extracellular | Members of this family adopt an immunoglobulin-like beta-sandwich, with seven strands in 2 beta sheets, in a Greek key topology. They are predominantly found in the extracellular portion of CD4 proteins, where they enable interaction with major histo ... | Domain |
A [auth G] | PF00516 | Envelope glycoprotein GP120 (GP120) | Envelope glycoprotein GP120 | - | Family |
C [auth B] | PF00001 | 7 transmembrane receptor (rhodopsin family) (7tm_1) | 7 transmembrane receptor (rhodopsin family) | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Pharos: Disease Associations Pharos Homepage Annotation
Membrane Protein Annotation: PDBTM PDBTM Database Homepage
Chains | External Link | Comment |
---|---|---|
PDBTM | Annotated as membrane protein by PDBTM |
Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage
Chains | External Link | Comment |
---|---|---|
MemProtMD | Annotated as membrane protein by MemProtMD |
Protein Modification Annotation
Modified Residue(s) | ||
---|---|---|
Chain | Residue(s) | Description |
C [auth B] | TYS | Parent Component: TYR :  AA0172 :  O4'-sulfo-L-tyrosine MOD:00181 |